Changes in NAWM and NAGM are crucial in MS progression, challenging the traditional lesion-centric model. Subtle alterations in myelin integrity, immune cell function, and neuronal connectivity ...

Using an animal model of multiple sclerosis (MS), researchers at the National Institutes of Health (NIH) have created a four-dimensional brain map that reveals how lesions similar to those seen in ...

NIH study reveals key players underlying disease onset and repair. Using an animal model of multiple sclerosis (MS), researchers at the National Institutes of Health (NIH) have created a ...

Multiple sclerosis (MS) is a chronic, often debilitating autoimmune disease that affects the central nervous system (CNS).

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the ...

In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF researchers found NfL in the bloodstream of patients who would ...

A study questioned the use of brain volume loss as a clinical trial endpoint in PPMS after finding a weak link to disability ...